Description

1. Question: Which neurotransmitter is involved with the reinforcing effects of nicotine?
2. Question: The PMHMP diagnosed a 12-year-old client with ADHD. The client‘s mother is hesitant to start any medication because she heard they were all addicted. The PMHMP states the client will be starting on extended release the minute. How does an extended release stimulant affect Dopamine transporter DAT occupancy to decrease risk of abuse and decreasing euphoria?
3. Question: Which SSRI is considered the best tolerated with the fewest CYP mediated drug interactions?
4. Question: Which antidepressant has FDA approval for the treatment of fibromyalgia and diabetic peripheral neuropathy?
5. Question: A client with a history of opioid use disorder and alcohol. Use disorder is committed to maintaining abstinence from both Which FDA approved medication has an indication for alcohol use disorder and would be appropriate for this client?
6. Question: Which medication promotes sleep by blocking histamine release?
7. Question: A client was offered a choice between naltrexone and acamprosate for medication assisted therapy for alcohol Use Which is the most accurate statement regarding these medication’s?
8. Question: The nurse practitioner is treating an adult client with major depressive disorder, history of alcohol, abuse, anxiety, and ADHD. Which of the following medications may improve symptoms of all comorbidities when augmented with an antidepressant and/or anxiolytic?
9. Question: A client with fibromyalgia reports filling a need to constantly move her legs while trying to sleep. Which medication class should be considered first?
10. Question: Which of the following best describes why adults with ADD/ADHD tend to have more comorbid mental health diagnoses than children?
11. Question: A 16-year-old female admits to eat in large quantities of food and spurts. She then takes diuretics and exercises strenuously to try to make up for the calories.
12. Question: Which medication is associated with risk of priapism?
13. Question: Which of the following clients would be at highest risk for increase suicidality with initiation of a prescription for fluoxetine?
14. Question: Clients were oppositional ADHD symptoms can be argumentative, disobedient, aggressive, and exempted and exhibit temper tantrums. These behaviors are hypothetically linked to low levels of epinephrine and dopamine in which area of the brain?
15. Question: An 87-year-old client with mild cognitive impairment is suspected of being in the early stage of Alzheimer’s disease. Although currently only used for research purposes, which biomarker evidence Support a diagnosis of Alzheimer’s disease?
16. Question: There are three stages of Alzheimer’s disease. Which stage involves cognitive or behavioral problems that interfere with function and every day activities?
17. Question: What is the most successful psychopharmacological approach to boost cholinergic functioning and memory in clients with Alzheimers disease?
18. Question: Which SSRI medication is FDA approved as a first line treatment for bulimia nervosa?
19. Question: When switching from a serotonergic drug to a MAOI. What is the appropriate timeframe to ensure a complete washout of the serotonergic drug?
20. Question: An 80-year-old man with a recent onset of dementia of the Alzheimer type has been treated for the last six months with galantamine 12 mg daily, but is still experiencing moderate deterioration. Treatment options for this client include, which of the following?
21. Question: A high school student has been taken Focalin for three months. The patient reports that the medication seems to have lost the efficacy. Which test should the PMHNP order?
22. Question: Which medication is the most appropriate choice for a client with motion sickness who needs short term assistance in falling asleep?
23. Question: A client taken MAOI has a blood pressure of 198/102 mmHg. What assessment question will the provider initially ask this client?
24. Question: Which addiction medication should be used with caution in the elderly?
25. Question: What is the mechanism of action for cannabis?
26. Question: The client with a six year history of smoking is considering nicotine replacement therapy to help her quit smoking, but has heard concerns about success rates from friends. Internet researches are confusing to the client. The PMHNP is the client which nicotine replacement therapy offers the highest rate of success?
27. Question: BUPRENORPHINE used an opioid detoxification and maintenance treatment. How is it used in this context?
28. Question: Rivastigmine a prescription drug used to treat dementia. What is its mechanism of action?
29. Question: A pregnant client is referred to the PMHNP for evaluation of safe medication assisted therapy use and pregnancy. Which medication should not be prescribed for this client?
30. Question: A disulfiram reaction, which occurs when the client ingests alcohol while taking disulfiram, includes which symptoms?
31. Question: Donepezil is a prescription drug used to treat dementia. What is its mechanism of action?
32. Question: Acamprostrate structurally resembles which neurotransmitter?
33. Question: Memantine is a prescription drug used to treat moderate to severe dementia related to Alzheimer’s disease. What is the mechanism of action?
34. Question: Blood pressure should be obtained—-ECG should be checked, especially in clients with known this rhythm is or clients older than 40 years of age—-serum sodium should be checked and older adults and clients on diuretic therapy——;
35. Question: A 70-year-old female with a history of afib and coronary artery disease is taking citalopram 20 mg daily. The client tells the PMHNP that she would like to discuss a dose increase. What is the most appropriate response by the PMHNP?
36. Question: Which of the following is an approved treatment for stimulant addiction?
37. Question: Which of the following medications provide the most options for delivery (chewable, sustain release, oral solution, and transdermal patch)?
38. Question: Which of the following statement guides, the selection of an alpha to agonist for the treatment of ADHD?
39. Question: A 17-year-old is thrilled when he wins an important high school championship. This natural high is most likely associated with inducing dopamine release in the amygdala and—-?
40. Question: Dementia medications are likely to cause I. distress. The PMHNP knows that G.I. side effects are most likely caused by which of the following?
41. Question: Which anti-depressant adjunct can cross the blood brain barrier and increase monoamine neurotransmitter levels?
42. Question: What is the mechanism of action for bupropion?
43. Question: Medications in which antidepressant category are effective, but not recommended as first line treatment due to the side effect profile?
44. Question: Which statement best describes the monoamine hypothesis of depression?
45. Question: The nurse practitioner is treating a client for ADHD who also has a history of cocaine addiction. The client asks for short acting stimulants. The nurse practitioner knows the extended release stimulant formulations have reduced abuse potential due to occupying the neural epinephrine trans enhance norepinephrine and dopamine signaling, and which area of the brain?
46. Question: Developmental issues, influence, ADHD symptoms and treatment. What symptoms are preschool children more likely to have?
47. Question: Which of the following medication should never be given at the same time as in MAOI?
48. Question: A pre-medical student with a family history of Alzheimer’s disease is interested in learning more about the brain regions involved in memory and the development of Alzheimer’s disease. The nurse practitioner describe the pathways of acetylcholine, an important nerotransmitter involved in dementia, noting that major cholinergic projections stem from the basal forebrain to the hippocampus, which are believed to be involved in memory.
49. Question: Which antidepressant is used as an adjunct to treatment for clients with depression who report continuing sleep difficulties?
50. Question: Which medication is a first line, treatment of aggression and agitation and dementia?
51. Question: The nurse practitioner prescribes Rivastigmine for a client with The client reports moderate G.I. side effects. What is the most appropriate course of action is to decrease G.I. side effects?
52. Question: A client presents with severe drinking problems, and the nurse practitioner affirms the need for pharmacological therapy. When the nurse practitioner suggested naltrexone the patient would like to know how this medication will help. Which explanation is the most appropriate?
53. Question: A client recently disclosed a 10 year prescription opioid addiction to the nurse practitioner. The client is quite functional, but continues seeking opiates to avoid withdrawal effects. Which of the following might the PMHNP tell the client about Potential for recovery?
54. Question: Which client newly diagnosed with depression would be most likely to respond well to an antidepressant medication?
55. Question: A client who has major depression with severe symptoms, begins taking an antidepressant Three weeks later, the client reports that the drug is not working. What action will the provider take to address the clients concerns?
56. Question: A 26-year-old client develops a dependence on opioids after taking them during and recovery from knee surgery. The client attempts to stop using them on their own, but when stopping or decreasing the dose experiences, nausea, muscle aches, sweating, heya, insomnia, and depression. The client and the nurse practitioner decided that, buprenorphine would be an appropriate treatment. Which strategy is appropriate for buprenorphine?
57. Question: Which receptors are affected by medication’s used to treat alcohol dependence?
58. Question: Individuals with ADHD smoke as frequently as adults w/ schizophrenia, twice the average of the typical adult population. Which statement best explains why nicotine may subjectively improve ADHD symptoms?
59. Question: A client taking Strattera for ADHD begins to neglect personal hygiene and does not want to see friends. What medication would be appropriate for this client?
60. Question: A 70 year old woman w/ dementia of the Alzheimer type has been tx w/ galantamine 12 mg twice daily for the last 3 years. She currently present to the clinic w/ symptoms of agitation and aggression toward her caregiver. The daughter has tried to redirect and give reassurance but these strategies have failed. Which of the following would be the most appropriate tx recommended to begin at bedtime to target agitation and aggression?
61. Question: Which medication Is not metabolized by CYP-450 enzyme?
62. Question: Atrophy of which 2 brain areas can lead to overactivity of the HPA axis?
63. Question: Sedative/hypnotic drugs (z drugs) are included within which scheduled medication categorty?
64. Question: which of the following statements is most accurate about the prescription of stimulant medications?
65. Question: A college student presents to the campus clinic w/ c/o great difficulty focusing which is leading to poor grades and possible academic failure. The student is referred to the PMHNP, who dx the student w/ The student states “I thought this was something that only happened to kids. Why do I have it now? Choose the best response.
66. Question: The PMHNP is educating the client regarding the role of psychopharmacology in the tx of dementia. The PMHNP must include what information?
67. Question: which medication can result in decreased lithium levels?
68. Question: A client dx w/ Alzheimer’s has decided to stop tx. The PMHNP has educated that medication discontinuation will result in return of cognitive symptoms and the medication may work as well if restarted. The client would still like to stop the medication due to the GI side effects. Which medication should not be stopped abruptly due to withdrawal effects?
69. Question: Which of the following medications would be contraindicated as a 1^st line ADHD tx for a client w/ comorbid anxiety?
70. Question: The spouse of a client w/ Alzheimer’s asks the provider for more information about the rivastigmine transdermal patch that is being used. After the discussion w/ the provider, which statement by the spouse indicates a need for further explanation?
71. Question: A client returns for a f/up appt and reports that all mental health symptoms have improved except for sleep difficulties. The client is having difficulty falling asleep and staying asleep. Which serotonergic medication is commonly prescribed at low doses as an adjunct for insomnia?
72. 72 Question: Disulfiram works by inhibiting the enzyme  which leads to elevated serum levels of acetaldehyde and initiation of the disulfiram-disulfiram-ethanol
73. Question: Which medication is contraindicated for use in clients w/ severe hepatic impairment?
74. Question: A client who take Sertraline 100 mg daily was recently prescribed Flexeril for whiplash injury by her She presents to the clinic w/ the following complaints: tremor, restlessness, & tachycardia. Symptoms are indicative of the following concerns?
75. Question: What is the rationale for instructing clients not to consume aged meats, cheeses, and soy products while taking MAOIs?